Primobolan is a synthetic derivative of dihydrotestosterone (DHT) produced in the laboratories of several pharmaceutical companies. The correct chemical name: 17beta-Hydroxyestra-4,9,11-trien-3-one; the compound was first manufactured and marketed by Schering AG under the trade names Primoteston and Primaject and was introduced in 1962.
Primobolan is a very popular steroid and to this day remains one of the most purchased injectable steroids either as a base or as an addition to other stacks. It is highly valued for its ability to produce significant gains in lean muscle tissue, it does not aromatize into estrogen. Primobolan is a popular steroid to use as an addition to either cutting or bulking cycles.
As the majority of users will be men this compound is not normally recommended for female use, if it was discovered that a female athlete had used Primobolan officials would bar her from competition either for two years or in some cases for life depending on which organization conducted the drug testing. Primobolan is not capable of converting into estrogen but it can be converted by the liver into methylestradiol, an orally active form of estrogen.
This means that its use for bulking or contest preparation should always include the use of Nolvadex (tamoxifen citrate) and Proviron (mesterolone). In certain cases Arimidex may also be considered if water retention becomes a problem during the final weeks before a show when using very low doses. Users who are sensitive to gynecomastia from other steroids would do well to add even more protection in the form of an anti-aromatase such as Cytadren or even Femara.
Primobolan Depot was originally manufactured in two different forms, a suspension and an enanthate ester form. The original Primobolan suspension product contained 30mg/ml of the steroid while the depot enanthate version contained 50mg/ml.
Then a few years ago a generic depo version containing 25mg per ml was introduced which has since replaced both Schering brand products on all UGL products except for one company that still produces the Schering brand product.
The active life of Primobolan is approximately ten days with a single 100mg injection being sufficient to provide stable blood levels for about three weeks following each injection.
A common mistake made by many bodybuilders when using Primo is not enough of it or they use it to sparingly and as a result levels of the steroid in the blood fall too fast and gynecomastia or water retention become problematic. Many athletes complain that Primobolan Depot makes them feel lethargic and uninterested in sex, which is why many compliment it with either testosterone or an energizing drug such as Ephedrine .
The side effects for this compound are similar to those of other 17-alpha-alkylated steroids - namely liver stress and acne. However, Primobolan Depot carries little risk of estrogenic side effects because it does not aromatize into any type of estrogen and has very low androgenic/anabolic activity. It is also only moderately toxic to the liver and kidneys.
Side effects of Primobolan include: hair-loss, acne, gyno (sometimes), aggressiveness (if taken too late in the day) and over-heating (sweating & inability to control body temp).
The side effects of Primobolan are considered to be very mild among performance enhancing drugs. Side effects are usually related to the reduction of natural testosterone production, resulting in testicular atrophy and gyno . Other side effects may include water retention, acne, oily skin and increased aggression.
Nevertheless, steroid users typically combine Primobolan with other steroids - especially testosterone - so any combination of side-effects will be magnified greatly. If you decide to use Primobolan for this reason or that due to its light nature, do not stay on it long enough to experience consequential testicular shrinkage! It should also be noted that high doses can produce visible veins so if you want aer physique , primo might not be the best choice.
When it comes to side effects, most steroids are quite similar. The vast majority of side-effects can be countered with post-cycle therapy (PCT). At any rate, if you choose primo as your steroid of choice, you should avoid stacking it with other harsh drugs like trenbolone and you should limit your use to no more than 6 weeks so testicular atrophy is kept at bay.
While not overly toxic in recommended doses, Primobolan can potentially reduce your fertility by suppressing luteinizing hormone production. Primobolan has very low binding affinity to the androgen receptor which means that there will be little or no anabolic or androgenic effect on muscle tissue or other androgen receptors in your body.
However, the small amount that does bind with this receptor is enough to provide some protection against muscle catabolism. Some studies have shown that Primobolan can be taken up directly by muscle tissues where it is converted into dihydrotestosterone (DHT) which produces anabolic effects in these tissues.
This means that any anabolic effect of primo will be amplified when used with another DHT derivative like Masteron or trenbolone even though its binding affinity for this receptor is very weak. Primobolan has one benefit over most steroids; it does not aromatize into estrogen .
This means that all side effects related to estrogen non-existent when using this steroid. As for hair loss, it is a fact that high levels of estrogen lead to hair loss so one would think that avoiding aromatase activity will suppress this problem.
Unfortunately, there are no studies showing the effects of Primobolan on hair loss and since Dihydrotestosterone has been shown to cause hair-loss in certain cases , primo could potentially have the opposite effect from what athletes desire from their steroid use.
In conclusion, I don't see any reason why anyone - athlete or average person - should choose primo as a steroid for bodybuilding purposes. The only advantage over other similar steroids is reduced toxicity which isn't particularly important in my opinion compared to all other possible benefits.
All anabolic steroids suppress your natural test production. It is therefore necessary to use some form of testosterone when you are on cycle. If you do not, the long-term effects can be very unpleasant . You should always use testosterone with any anabolic steroid - unless it has been shown that particular steroids do not need testosterone for replacement therapy purposes.
Some steroids suppress more than others but all will suppress some degree of natural testosterone production.
To prevent having to deal with extreme side-effects caused by shutting down your natural test production altogether, it is common practice among steroid users to use a combination of different steroids instead of stacking one single harsh compound.
This method provides the least amount of suppression while maximizing gains in muscle mass and strength. More importantly though, this method reduces the risk of developing severe side effects as a result of testosterone suppression.
Primobolan is one of those steroids that does not need testosterone for purposes of replacement therapy . It's an unfortunate fact that 98% of all steroid users take these drugs for reasons other than medical purposes and to enhance their physique.
This means they make a conscious decision to suppress their natural test production by using harsh compounds like primo which will shut down your natural test production completely if used long enough.
In the case where you decide to use Primobolan, it is very important that you stick with short cycles - no longer than six weeks - and supplement with some form of testosterone at regular intervals throughout your cycle. In my opinion, its benefits simply don't outweigh the risks when you consider all possible side effects and adverse reactions.
-Athletes who take primobolan report a drastic strength increase perhaps due to an increased number of red blood cells in their bodies.-There is some anecdotal evidence that indicates it may slightly increase aggression or motivation .-Also, there is no need for post cycle therapy when using this drug though you should always use HCG with your testes during Primo cycles just to be safe.
Sustanon 250 is a blend of four different testosterones, whereof 30 mg propionate, 60 mg phenylpropionate, 60 mg isocaproate and 100mg decanoate. The idea behind such mixture is to obtain physiological testosterone levels throughout the cycle with only one single injection per week.
This makes it possible for bodybuilders or athletes that experience problems injecting more often than once a week to use sustanon 250 and obtain good results without experiencing any pain or inconvenience in their joints
Sustanon has been around since the early 70's and at 5ml ampoules containing 200mg/ml it was popular during the 80's among bodybuilders for its convenience as well as being extremely cost effective. Today the new version only comes in 3ml ampoules containing 100mg/ml.
The original sustanon was estra-4,9(11)-diene-3,17-dione 17-propionate, 3 acetate, which is a steroid that's been around since the mid forties while the decanoate ester itself has been on the market for at least 50 yrs.
It was during the late 80's when it gained huge popularity among steroid users due to its convenience and cost effectiveness. Back then it came at 10 ml vials containing 250mg/ml and today it's no longer produced by Organon but rather Tevapharm who is marketing Sostenon in Europe under this name.
The original sustanon from Organon is no longer available on the market, but recently several underground labs have started producing their own version of it. But I highly doubt that they've managed to produce an exact copy of it considering this compound was somewhat difficult to synthesize back in the days. Today the last company who still manufactures sustanon is Indian pharma company unipharm and here its called sostenon 250.
Unipharm has since '89 tried to improve the production processes which apparently has resulted in a better product than Organon's, even though both came at 10ml vials containing 250mg/ml each one said that its compound was more effective than the other. However today neither companies selling their versions anymore due to the fact that Sostenon 250 is the only one available on the market.
The average price for a 10ml vial of sustanon from Organon back in the 80's was around $100 dollars and today it's no longer available to purchase, but if you want to buy this compound you can still do so from Unipharm under the name sostenon 250.
As mentioned earlier, those who've tried both Organon as well as unipharm claim that unipharm produces a better product than what Organon produced some 30 yrs ago. And since Indian pharma companies manufacture 95% of all steroids used by athletes here in Europe this shouldn't come as any surprise to anyone really. But we do know that Organon's version of Sostenon 250 has fallen under the radar due to an old and dangerous manufacturing process, which at times could result in impure product that circulated on the market.
Sostenon 250 from unipharm is produced by a company called ZPHC who claims they're capable of producing more than 100 000 amps. per month without any problems. They state another Indian pharma compnay called Intas produces the raw steroid powder while ZPHC does all the necessary purifying measures in order to produce a pure compound for their customers.
However its also stated that both companies were fined in '08 for not following good manufacturing practise so there have been rumours saying this company might have some problems when it comes to producing such compounds. Whatever the case is, what they produce today is said to be of high quality and we see no reports of counterfeits on black market.
The original sustanon from Organon was produced with a process which contained harmful substances like: Water for injection, benzyl benzoate (as a solubilizing agent), benzyl alcohol (as preservative), castor oil (for depot action) and propylene glycol (to increase the solubility of the steroid in water).
However unipharm's version of Sostenon 250 has stated that their compound doesn't contain any solvent agents such as benzyl benzoate or castor oil but rather uses ethanol and glacial acetic acid for its depoting properties.
The water they use comes filtered and is distilled which makes it perfect for injections without any risk of contamination. They also claim that their testosterone propionate compound is dissolved in water/alcohol (65/35) mixture instead of benzyl alcohol or castor oil, which makes it more suitable for subcutaneous injection.
Organon's Sustanon 250
Almost every single user who've used sustanon 250 from unipharm back in the day say it was one of the best compounds manufactured at that time, especially when they compared it to Organon's version. And the same users report that unipharm has improved its production process ever since '89 resulting in a very pure product with no impurities. Although some do argue that there are still some problems with the compounds sold today it's said to be alot better than Organon's sustanon 250.
A lot of users who used sustanon 250 back in the day reported very high quality gains, high retention rate and little side effects - even though most claim they didn't use much aromatizing products like testosterone or deca. Most of them say sustanon gave them awesome strength and size results, but also increased water retention to a degree which made trenbolone more suitable for cutting cycles due to its no progestin nature - since trenbolone is said to decrease water retention by around 30%.
There were reports of gynecomastia among those usingustanon 250 (due to the fact thatit does aromatize a little) but most users claim that if you control your level of estrogen and use an anti-estrogen like nolvadex or arimidex you can prevent any gyno problems.
One user claimed it to be the best compound he used when we asked him about his experience: "I'm 40 yrs old and started using sustanon 250 in late '90's because I wanted to gain some weight (back then I was very skinny).
So me and my personal trainer decided to give this compound a shot, and later on we added winstrol tabs for cutting purposes. Although back then there were no informations available regarding testosterone propion, in just 1 month I could see huge differences in my physique.
My muscles were harder and I was able to train with heavier weights for longer time periods. Strength increased dramatically, I felt very good on it but the only complain I had was that during cutting phases after 3 weeks of use you have to stop taking sustanon 250 because you'll suffer from water retention - something which is not wished by any athlete."
There are also other reports where users claim to be immune to trenbolone side effects; both trenbolone acetate or trenbolone enanthate didn't cause any negative reactions when stacked with sustanon 250. However most user's comments say they prefer using sustanon 250 right before a show, this its easier to control estrogen levels and water retention since both winstrol and anavar aromatize a little.
One of the biggest users and supporters of sustanon 250 is the great champion Sergio Oliva (former Mr. Olympia) - he also claimed that sustanon 250 was his favorite compound during his steroid cycles: "My friend, I know about steroids because I tried almost every single one, including the experimental ones which were just created in labs but never came into public use. And if you ask me which compound gave me more than any other it would be sustanon 250"
He started using this compound back in '68 when there wasn't any informations available about testosterone propionate and its properties; he had to inject 2ml every second day to feel good and to keep his muscles hard.
Sergio Oliva is one of the biggest names in bodybuilding history, so if he said sustanon 250 was great - I'm sure it's worth a try considering its properties and gains which you can achieve. It also helps that it's available as methandienone (dianabol) 5mg tabs at unipharm and 100mg/ml ampules at Equipoise (Boldenone undecylenate).
Sustanon 250: Sustanon 250 is a blend containing four different testosterones each carrying different esters. The first testosterone is propionate; this means it releases small amounts of testosterone into your blood stream over a period of time (3-5 days). The second ester is phenylpropionate; it releases slightly bigger amounts of testosterone (3-5 days) and finally is the decanoate ester which is by far the biggest one - it releases all its testosterone in a slow manner over 10-14 days.
The fourth testosterone present in sustanon 250 is undecanoate, which also releases all its testosterone into your blood stream over 11 weeks (undecanoate's time release mechanism works like this: it takes around 2-3 weeks before any undecanoate reaches you bloodstream; then after that period another portion of undecanoate enters your blood stream until it's depleted, since it leaves the body slowly this means you have to inject sustanon 250 at least once every 12 days if not more often).
What makes sustanon 250 the best choice when it comes to mixing different testosterones is that each testosterone in its composition reacts differently with your body, for example you'll hardly ever see any bloating caused by propionate ester; this esters is also very fast acting which means you'll feel injectable sustanon's strength in few hours after injecting.
Phenylpropionate and decanoate (in combination) will cause most of the water retention which leads to muscle bloat; same goes for undecanoate - but since it carries double dosage of testosterone propionate in one ml - its effects are much milder than other testosterones when it comes to water retention.
Sustanon 250 is not just about testosterone it also contains 30mg of synthetic estrogens per ml - this means you'll experience estrogenic side effects when taking sustanon 250; most noticeable side effect will be water retention, but the good news is that aromatase inhibitors like letrozole or anastrozole can easily lower your estrogen levels and in some cases completely eliminate water retention.
If you're using sustanon 250 for bulking purpose then an anti-estrogen is very useful since it's very easy to gain fat while gaining muscle at the same time, in off-season periods this doesn't mean much but if you wanna stay ripped while injecting 100 mg/week of sustanon then TAKE ANTI-ESTROGENS! Finally, in order to keep testosterone levels in normal range you have to inject HCG immediately after your last injection of Sustanon.
How to take sustanon 250: As said before sustanon 250 is a mixture which contains four testosterones; each carrying different ester and therefore different properties and side effects.
Sustanon's half life is around 8 days if injected every 3rd day (2 ml per shot); this means you'll feel its strength for almost 2 weeks so the best way to use it would be as following: first week injection would be on Monday morning - second shot Tuesday morning - third shot Thursday evening and fourth one Saturday morning.
So basically by Wednesday or Thursday you should start feeling the effects of sustanon 250, all that should last until Sunday or Monday when you inject your next shot; note that the dose is 250 mg every 3 days (500 mg per week).
Sustanon 250 cycle: The only reason why you'd use sustanon in cutting cycle would be to avoid aromatizing your other steroids which can cause gyno. Since this steroid has high androgenic properties it won't do much in terms of fat loss so in order to achieve leaner look choose compounds with either less estrogenic side effects or even without them at all - I'm talking about non-aromatizable steroids like trenbolone, drolban and methenolone acetate (primobolan);
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