Primobolan is a synthetic derivative of dihydrotestosterone (DHT) produced in the laboratories of several pharmaceutical companies. The correct chemical name: 17beta-Hydroxyestra-4,9,11-trien-3-one; the compound was first manufactured and marketed by Schering AG under the trade names Primoteston and Primaject and was introduced in 1962.
Primobolan is a very popular steroid and to this day remains one of the most purchased injectable steroids either as a base or as an addition to other stacks. It is highly valued for its ability to produce significant gains in lean muscle tissue, it does not aromatize into estrogen. Primobolan is a popular steroid to use as an addition to either cutting or bulking cycles.
As the majority of users will be men this compound is not normally recommended for female use, if it was discovered that a female athlete had used Primobolan officials would bar her from competition either for two years or in some cases for life depending on which organization conducted the drug testing. Primobolan is not capable of converting into estrogen but it can be converted by the liver into methylestradiol, an orally active form of estrogen.
This means that its use for bulking or contest preparation should always include the use of Nolvadex (tamoxifen citrate) and Proviron (mesterolone). In certain cases Arimidex may also be considered if water retention becomes a problem during the final weeks before a show when using very low doses. Users who are sensitive to gynecomastia from other steroids would do well to add even more protection in the form of an anti-aromatase such as Cytadren or even Femara.
Primobolan Depot was originally manufactured in two different forms, a suspension and an enanthate ester form. The original Primobolan suspension product contained 30mg/ml of the steroid while the depot enanthate version contained 50mg/ml.
Then a few years ago a generic depo version containing 25mg per ml was introduced which has since replaced both Schering brand products on all UGL products except for one company that still produces the Schering brand product.
The active life of Primobolan is approximately ten days with a single 100mg injection being sufficient to provide stable blood levels for about three weeks following each injection.
A common mistake made by many bodybuilders when using Primo is not enough of it or they use it to sparingly and as a result levels of the steroid in the blood fall too fast and gynecomastia or water retention become problematic. Many athletes complain that Primobolan Depot makes them feel lethargic and uninterested in sex, which is why many compliment it with either testosterone or an energizing drug such as Ephedrine .
The side effects for this compound are similar to those of other 17-alpha-alkylated steroids - namely liver stress and acne. However, Primobolan Depot carries little risk of estrogenic side effects because it does not aromatize into any type of estrogen and has very low androgenic/anabolic activity. It is also only moderately toxic to the liver and kidneys.
Side effects of Primobolan include: hair-loss, acne, gyno (sometimes), aggressiveness (if taken too late in the day) and over-heating (sweating & inability to control body temp).
The side effects of Primobolan are considered to be very mild among performance enhancing drugs. Side effects are usually related to the reduction of natural testosterone production, resulting in testicular atrophy and gyno . Other side effects may include water retention, acne, oily skin and increased aggression.
Nevertheless, steroid users typically combine Primobolan with other steroids - especially testosterone - so any combination of side-effects will be magnified greatly. If you decide to use Primobolan for this reason or that due to its light nature, do not stay on it long enough to experience consequential testicular shrinkage! It should also be noted that high doses can produce visible veins so if you want aer physique , primo might not be the best choice.
When it comes to side effects, most steroids are quite similar. The vast majority of side-effects can be countered with post-cycle therapy (PCT). At any rate, if you choose primo as your steroid of choice, you should avoid stacking it with other harsh drugs like trenbolone and you should limit your use to no more than 6 weeks so testicular atrophy is kept at bay.
While not overly toxic in recommended doses, Primobolan can potentially reduce your fertility by suppressing luteinizing hormone production. Primobolan has very low binding affinity to the androgen receptor which means that there will be little or no anabolic or androgenic effect on muscle tissue or other androgen receptors in your body.
However, the small amount that does bind with this receptor is enough to provide some protection against muscle catabolism. Some studies have shown that Primobolan can be taken up directly by muscle tissues where it is converted into dihydrotestosterone (DHT) which produces anabolic effects in these tissues.
This means that any anabolic effect of primo will be amplified when used with another DHT derivative like Masteron or trenbolone even though its binding affinity for this receptor is very weak. Primobolan has one benefit over most steroids; it does not aromatize into estrogen .
This means that all side effects related to estrogen non-existent when using this steroid. As for hair loss, it is a fact that high levels of estrogen lead to hair loss so one would think that avoiding aromatase activity will suppress this problem.
Unfortunately, there are no studies showing the effects of Primobolan on hair loss and since Dihydrotestosterone has been shown to cause hair-loss in certain cases , primo could potentially have the opposite effect from what athletes desire from their steroid use.
In conclusion, I don't see any reason why anyone - athlete or average person - should choose primo as a steroid for bodybuilding purposes. The only advantage over other similar steroids is reduced toxicity which isn't particularly important in my opinion compared to all other possible benefits.
All anabolic steroids suppress your natural test production. It is therefore necessary to use some form of testosterone when you are on cycle. If you do not, the long-term effects can be very unpleasant . You should always use testosterone with any anabolic steroid - unless it has been shown that particular steroids do not need testosterone for replacement therapy purposes.
Some steroids suppress more than others but all will suppress some degree of natural testosterone production.
To prevent having to deal with extreme side-effects caused by shutting down your natural test production altogether, it is common practice among steroid users to use a combination of different steroids instead of stacking one single harsh compound.
This method provides the least amount of suppression while maximizing gains in muscle mass and strength. More importantly though, this method reduces the risk of developing severe side effects as a result of testosterone suppression.
Primobolan is one of those steroids that does not need testosterone for purposes of replacement therapy . It's an unfortunate fact that 98% of all steroid users take these drugs for reasons other than medical purposes and to enhance their physique.
This means they make a conscious decision to suppress their natural test production by using harsh compounds like primo which will shut down your natural test production completely if used long enough.
In the case where you decide to use Primobolan, it is very important that you stick with short cycles - no longer than six weeks - and supplement with some form of testosterone at regular intervals throughout your cycle. In my opinion, its benefits simply don't outweigh the risks when you consider all possible side effects and adverse reactions.
-Athletes who take primobolan report a drastic strength increase perhaps due to an increased number of red blood cells in their bodies.-There is some anecdotal evidence that indicates it may slightly increase aggression or motivation .-Also, there is no need for post cycle therapy when using this drug though you should always use HCG with your testes during Primo cycles just to be safe.